General Ingredient Research — not an evaluation of this product
The research summaries below are about the ingredients in general, drawn from published studies that often use different doses, forms, and populations than this product. A "strong" evidence rating for an ingredient does not mean this product will produce that effect — studied doses may be significantly higher or lower than what is contained here. Always verify doses against the Supplement Facts table above.
strongSupports bone healthPrimary structural component of bones. Adequate lifelong intake, combined with vitamin D, helps prevent osteoporosis — supported by extensive clinical evidence.
strongSupports muscle functionEssential for muscle contraction through calcium signaling.
moderateSupports sleep qualityMay improve sleep quality, especially in older adults and those with low magnesium status.
strongSupports bone health60% of body magnesium is stored in bone. Essential for bone mineralization.
moderateSupports muscle recoveryMay reduce muscle cramps and support post-exercise recovery.
strongAntioxidant protectionProtects polyunsaturated fatty acids in cell membranes from oxidation.
moderateSupports skin healthMay help protect skin from UV damage when combined with vitamin C.
moderateSupports cholesterol levelsAt pharmacological doses (1500-3000mg), niacin may improve HDL cholesterol. This effect is dose-dependent and not expected at typical supplement doses.
strongSupports energy metabolismEssential coenzyme (NAD/NADP) in hundreds of metabolic reactions.
strongSupports iron levelsIron supplementation is used to address iron deficiency. Should be taken under medical supervision as excess iron can be harmful.
strongSupports energy levelsIron is essential for oxygen transport and cellular energy production.
strongAnti-inflammatoryCurcumin has anti-inflammatory properties in clinical studies, though bioavailability is low without enhanced formulations (piperine, liposomal, etc.).
moderateSupports joint healthCurcumin may reduce joint pain and inflammation in osteoarthritis. Effects depend on bioavailability — enhanced forms (BCM-95, Meriva, piperine) show better results than standard curcumin.
strongReduces stress and anxietyMultiple RCTs show cortisol reduction and improved stress/anxiety scores, primarily with standardized extracts (KSM-66, Sensoril) at 300-600mg/day.
moderateMay improve testosteroneLimited evidence for testosterone effects, primarily in stressed or subfertile men using KSM-66 extract. Results in healthy men are inconsistent.
moderateSupports athletic performanceMay improve VO2 max, strength, and recovery. Typically studied at 300-600mg/day of standardized root extract (KSM-66 or equivalent).
strongReduces stress and anxietyMultiple RCTs show cortisol reduction and improved stress/anxiety scores, primarily with standardized extracts (KSM-66, Sensoril) at 300-600mg/day.
moderateMay improve testosteroneLimited evidence for testosterone effects, primarily in stressed or subfertile men using KSM-66 extract. Results in healthy men are inconsistent.
moderateSupports athletic performanceMay improve VO2 max, strength, and recovery. Typically studied at 300-600mg/day of standardized root extract (KSM-66 or equivalent).
strongReduces stress and anxietyMultiple RCTs show cortisol reduction and improved stress/anxiety scores, primarily with standardized extracts (KSM-66, Sensoril) at 300-600mg/day.
moderateMay improve testosteroneLimited evidence for testosterone effects, primarily in stressed or subfertile men using KSM-66 extract. Results in healthy men are inconsistent.
moderateSupports athletic performanceMay improve VO2 max, strength, and recovery. Typically studied at 300-600mg/day of standardized root extract (KSM-66 or equivalent).