| Ingredient | Amount | % DV% Daily Value — how much of the recommended daily intake one serving provides, based on a 2,000 calorie diet. 100% = full daily need. Values over 100% are common for water-soluble vitamins (B, C) and generally safe. Values over 200% are highlighted. |
|---|---|---|
| Niacin | 100 mg | 500% |
| Vitamin B6 | 20 mg | 1000% |
| Calcium | 95 mg | 10% |
| Magnesium | 100 mg | 25% |
| Copper | 260 mcg | 13% |
| Potassium | 50 mg | 1% |
| White Willow (Salix alba) Bark Extract 4:1 | 225 mg | — |
| Passionflower (Passiflora incarnata) Flower Extract 4:1 | 160 mg | — |
| Bromelain | 150 mg | — |
| Wild Yam | 150 mg | — |
| Valerian | 120 mg | — |
| Black Cohosh | 75 mg | — |
| Hops (Humulus lupulus) Strobile Extract 5:1 | 60 mg | — |
| Valerian (Valeriana officinalis) Root Extract 5:1 | 60 mg | — |
| L-Glutamic Acid | 25 mg | — |
Other ingredients: Vegetable Capsule, Citric Acid, Magnesium Stearate
This score evaluates label quality — dosage disclosure, transparency, cleanliness of inactive ingredients, and formula composition. It does not measure clinical efficacy, bioavailability, or third-party testing. Read full methodology
Same category, higher SupplementScore. Based on dosage transparency, label cleanliness, and formula quality.
The research summaries below are about the ingredients in general, drawn from published studies that often use different doses, forms, and populations than this product. A "strong" evidence rating for an ingredient does not mean this product will produce that effect — studied doses may be significantly higher or lower than what is contained here. Always verify doses against the Supplement Facts table above.
Primary structural component of bones. Adequate lifelong intake, combined with vitamin D, helps prevent osteoporosis — supported by extensive clinical evidence.
Essential for muscle contraction through calcium signaling.
May improve sleep quality, especially in older adults and those with low magnesium status.
60% of body magnesium is stored in bone. Essential for bone mineralization.
May reduce muscle cramps and support post-exercise recovery.
Involved in neurotransmitter synthesis including serotonin and dopamine. Cofactor for over 100 enzyme reactions.
No reviews yet.
All scores are algorithmically generated from publicly available label data (NIH Dietary Supplement Label Database) and reflect label quality — not clinical efficacy, safety, or product quality. This page is not affiliated with or endorsed by Integrative Therapeutics. If you represent this brand and believe any information is inaccurate, please contact us for a correction. Read full methodology
Alternatives are selected from the same category (B Vitamins) with a higher overall score. This is not a recommendation — always verify ingredients and dosages match your needs.
B6 is a cofactor in the transsulfuration pathway, converting homocysteine to cysteine. This is a separate pathway from the B12/folate remethylation route.
At pharmacological doses (1500-3000mg), niacin may improve HDL cholesterol. This effect is dose-dependent and not expected at typical supplement doses.
Essential coenzyme (NAD/NADP) in hundreds of metabolic reactions.