| Ingredient | Amount | % DV% Daily Value — how much of the recommended daily intake one serving provides, based on a 2,000 calorie diet. 100% = full daily need. Values over 100% are common for water-soluble vitamins (B, C) and generally safe. Values over 200% are highlighted. |
|---|---|---|
| Niacin | 37 mg | 185% |
| Vitamin B6 | 23 mg | 1150% |
| Calcium | 39 mg | 4% |
| Magnesium | 37 mg | 9% |
| Valerian (Valeriana officinalis) Root Extract | 375 mg | — |
| Hops (Humulus lupulus) strobile extract | 300 mg | — |
| Jujube (Ziziphus jujuba) Seed Extract | 300 mg | — |
| Passionflower (Passiflora incarnata) Aerial Parts Extract | 300 mg | — |
| Skullcap (Scutellaria lateriflora) Aerial Parts Extract 4:1 | 262 mg | — |
| L-Theanine | 90 mg | — |
Other ingredients: Vegetable Polysaccharide Capsule, Ascorbyl Palmitate, Cellulose
This score evaluates label quality — dosage disclosure, transparency, cleanliness of inactive ingredients, and formula composition. It does not measure clinical efficacy, bioavailability, or third-party testing. Read full methodology
Same category, higher SupplementScore. Based on dosage transparency, label cleanliness, and formula quality.
The research summaries below are about the ingredients in general, drawn from published studies that often use different doses, forms, and populations than this product. A "strong" evidence rating for an ingredient does not mean this product will produce that effect — studied doses may be significantly higher or lower than what is contained here. Always verify doses against the Supplement Facts table above.
Primary structural component of bones. Adequate lifelong intake, combined with vitamin D, helps prevent osteoporosis — supported by extensive clinical evidence.
Essential for muscle contraction through calcium signaling.
May improve sleep quality, especially in older adults and those with low magnesium status.
60% of body magnesium is stored in bone. Essential for bone mineralization.
May reduce muscle cramps and support post-exercise recovery.
Involved in neurotransmitter synthesis including serotonin and dopamine. Cofactor for over 100 enzyme reactions.
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All scores are algorithmically generated from publicly available label data (NIH Dietary Supplement Label Database) and reflect label quality — not clinical efficacy, safety, or product quality. This page is not affiliated with or endorsed by Integrative Therapeutics. If you represent this brand and believe any information is inaccurate, please contact us for a correction. Read full methodology
Alternatives are selected from the same category (B Vitamins) with a higher overall score. This is not a recommendation — always verify ingredients and dosages match your needs.
B6 is a cofactor in the transsulfuration pathway, converting homocysteine to cysteine. This is a separate pathway from the B12/folate remethylation route.
At pharmacological doses (1500-3000mg), niacin may improve HDL cholesterol. This effect is dose-dependent and not expected at typical supplement doses.
Essential coenzyme (NAD/NADP) in hundreds of metabolic reactions.