Pyridoxal-Alpha-Ketoglutarate

Also known as: pyridoxine, pyridoxal, pyridoxamine, pyridoxine hcl

Water-soluble vitamin involved in over 100 enzyme reactions, primarily in protein metabolism. Important for brain development, immune function, and hemoglobin production.

1.3mgRDARecommended Dietary Allowance — the daily intake sufficient for 97-98% of healthy adults. Set by the National Institutes of Health.

100mgUpper LimitTolerable Upper Intake Level (UL) — the maximum daily dose unlikely to cause adverse health effects. Exceeding this consistently may increase toxicity risk.

2ProductsNumber of supplements in our database that contain this ingredient.

2Health ClaimsNumber of researched health benefits associated with this ingredient, rated by evidence strength (strong/moderate/weak).

2Side EffectsNumber of documented side effects from clinical literature and adverse event reports.

Health Claims & Evidence

moderateSupports brain function

Involved in neurotransmitter synthesis including serotonin and dopamine.

0 studies on PubMed

strongMay reduce homocysteine

Cofactor in the transsulfuration pathway, converting homocysteine to cysteine (separate from B12/folate remethylation pathway).

0 studies on PubMed

Known Side Effects

nerve damage at very high doses (>200mg/day long-term)
nausea

Drug Interactions

levodopa
phenytoin
cycloserine

Always consult your healthcare provider before combining supplements with medications.

Products Containing Pyridoxal-Alpha-Ketoglutarate (2)

Douglas LaboratoriesSplit Dose Ultra Evening Meal P.M.

77 2

Douglas LaboratoriesSplit Dose Ultra Morning Meal AM