| Ingredient | Amount | % DV% Daily Value — how much of the recommended daily intake one serving provides, based on a 2,000 calorie diet. 100% = full daily need. Values over 100% are common for water-soluble vitamins (B, C) and generally safe. Values over 200% are highlighted. |
|---|---|---|
| Vitamin E | 15 IU | 50% |
| Niacin | 23 mg | 115% |
| Folic Acid | 225 mcg | 56% |
| Vitamin B12 | 120 mcg | 2000% |
| Manganese | 7 mg | 350% |
| Fish Oils | 3180 mg | — |
| Glucosamine Sulfate | 1500 mg | — |
| Chondroitin Sulfate | 1200 mg | — |
| Flaxseed Oil | 150 mg | — |
| MSM | 150 mg | — |
| Indian Frankincense extract | 115 mg | — |
| Stinging Nettle extract | 70 mg | — |
| Turmeric extract | 40 mg | — |
| Alpha-Lipoic Acid | 5 mg | — |
| BioPerine Complex | 6 mg | — |
Other ingredients: Gelatin, purified Water, Glycerin, Soy Lecithin, Annatto, Titanium Dioxide, Beeswax, St. John's Bread, Turmeric
This score evaluates label quality — dosage disclosure, transparency, cleanliness of inactive ingredients, and formula composition. It does not measure clinical efficacy, bioavailability, or third-party testing. Read full methodology
Same category, higher SupplementScore. Based on dosage transparency, label cleanliness, and formula quality.
The research summaries below are about the ingredients in general, drawn from published studies that often use different doses, forms, and populations than this product. A "strong" evidence rating for an ingredient does not mean this product will produce that effect — studied doses may be significantly higher or lower than what is contained here. Always verify doses against the Supplement Facts table above.
Essential for red blood cell formation. Deficiency causes megaloblastic anemia, confirmed by decades of clinical evidence.
Involved in myelin synthesis and nerve function. Adequate B12 status supports neurological health, particularly in older adults and vegans.
Cofactor in energy production pathways, but supplementation only helps if deficient.
Protects polyunsaturated fatty acids in cell membranes from oxidation.
May help protect skin from UV damage when combined with vitamin C.
At pharmacological doses (1500-3000mg), niacin may improve HDL cholesterol. This effect is dose-dependent and not expected at typical supplement doses.
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All scores are algorithmically generated from publicly available label data (NIH Dietary Supplement Label Database) and reflect label quality — not clinical efficacy, safety, or product quality. This page is not affiliated with or endorsed by Irwin Naturals. If you represent this brand and believe any information is inaccurate, please contact us for a correction. Read full methodology
Alternatives are selected from the same category (B Vitamins) with a higher overall score. This is not a recommendation — always verify ingredients and dosages match your needs.
Essential coenzyme (NAD/NADP) in hundreds of metabolic reactions.
Curcumin has anti-inflammatory properties in clinical studies, though bioavailability is low without enhanced formulations (piperine, liposomal, etc.).
Curcumin may reduce joint pain and inflammation in osteoarthritis. Effects depend on bioavailability — enhanced forms (BCM-95, Meriva, piperine) show better results than standard curcumin.
May support cardiovascular health by influencing triglyceride levels. Effect is dose-dependent (typically studied at 1-4g EPA+DHA/day).
EPA and DHA have anti-inflammatory properties through multiple pathways. Effects are dose-dependent, typically studied at 1-3g combined EPA+DHA/day.
DHA is a structural component of brain tissue. Supplementation may support cognitive health, primarily studied at 500-1000mg DHA/day in older adults.
Adequate folate intake before and during early pregnancy reduces risk of neural tube defects. This is one of the most well-established findings in nutrition.
Essential cofactor for nucleotide synthesis and cell division.
Adequate folate intake before and during early pregnancy reduces risk of neural tube defects. This is one of the most well-established findings in nutrition.
Essential cofactor for nucleotide synthesis and cell division.
Curcumin has anti-inflammatory properties in clinical studies, though bioavailability is low without enhanced formulations (piperine, liposomal, etc.).
Curcumin may reduce joint pain and inflammation in osteoarthritis. Effects depend on bioavailability — enhanced forms (BCM-95, Meriva, piperine) show better results than standard curcumin.
No FDA warnings or recalls on file.