| Ingredient | Amount | % DV% Daily Value — how much of the recommended daily intake one serving provides, based on a 2,000 calorie diet. 100% = full daily need. Values over 100% are common for water-soluble vitamins (B, C) and generally safe. Values over 200% are highlighted. |
|---|---|---|
| Potassium Phosphate | NP | — |
| Betaine | NP | — |
| Choline Bitartrate | NP | — |
| Mg Malate | NP | — |
| Ascorbic | NP | — |
| Zn Chelate | NP | — |
| Niacinamide | NP | — |
| Green Tea | NP | — |
| Curcumin | NP | — |
| Astragalus | NP | — |
| Calcium Pyruvate | NP | — |
| Theanine | NP | — |
| Red Clover | NP | — |
| RNA | NP | — |
| Pyridoxine | NP | — |
| Alpha Keto Glutarate | NP | — |
| Carnosine | NP | — |
| Riboflavin 5-Phosphate | NP | — |
| Boron Chelate | NP | — |
| Selenomethionine | NP | — |
| Citrus Bioflavonoid | NP | — |
| Carnitine | NP | — |
| D-Ribose | NP | — |
| Pedra Hume Caa | NP | — |
| Cyani | NP | — |
| Huckleberry | NP | — |
| Allantoin | NP | — |
| Folic Acid | NP | — |
| Vitamin B12 | NP | — |
| Intrinsic Factor | NP | — |
| Molybdenum Chelate | NP | — |
| Biotin | NP | — |
| 5 Methyltetrahydrofolate | NP | — |
Other ingredients: Water, Natural Flavors, Ethanol, Glycerin
This score evaluates label quality — dosage disclosure, transparency, cleanliness of inactive ingredients, and formula composition. It does not measure clinical efficacy, bioavailability, or third-party testing. Read full methodology
Same category, higher SupplementScore. Based on dosage transparency, label cleanliness, and formula quality.
The research summaries below are about the ingredients in general, drawn from published studies that often use different doses, forms, and populations than this product. A "strong" evidence rating for an ingredient does not mean this product will produce that effect — studied doses may be significantly higher or lower than what is contained here. Always verify doses against the Supplement Facts table above.
Adequate folate intake before and during early pregnancy reduces risk of neural tube defects. This is one of the most well-established findings in nutrition.
Essential cofactor for nucleotide synthesis and cell division.
Essential for red blood cell formation. Deficiency causes megaloblastic anemia, confirmed by decades of clinical evidence.
Involved in myelin synthesis and nerve function. Adequate B12 status supports neurological health, particularly in older adults and vegans.
Cofactor in energy production pathways, but supplementation only helps if deficient.
Limited evidence. May help in cases of biotin deficiency but most people get adequate amounts from diet.
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All scores are algorithmically generated from publicly available label data (NIH Dietary Supplement Label Database) and reflect label quality — not clinical efficacy, safety, or product quality. This page is not affiliated with or endorsed by Systemic Formulas. If you represent this brand and believe any information is inaccurate, please contact us for a correction. Read full methodology
Alternatives are selected from the same category (B Vitamins) with a higher overall score. This is not a recommendation — always verify ingredients and dosages match your needs.
Essential cofactor for carboxylases involved in gluconeogenesis, fatty acid synthesis, and amino acid catabolism.
Primary structural component of bones. Adequate lifelong intake, combined with vitamin D, helps prevent osteoporosis — supported by extensive clinical evidence.
Essential for muscle contraction through calcium signaling.
Adequate folate intake before and during early pregnancy reduces risk of neural tube defects. This is one of the most well-established findings in nutrition.
Essential cofactor for nucleotide synthesis and cell division.
Adequate folate intake before and during early pregnancy reduces risk of neural tube defects. This is one of the most well-established findings in nutrition.
Essential cofactor for nucleotide synthesis and cell division.
Supports immune cell function. Regular supplementation may modestly reduce cold duration, but does not prevent colds.
Potent water-soluble antioxidant that protects cells from oxidative damage.
Essential cofactor for enzymes involved in collagen production.
Involved in neurotransmitter synthesis including serotonin and dopamine.
Cofactor in the transsulfuration pathway, converting homocysteine to cysteine (separate from B12/folate remethylation pathway).
At pharmacological doses (1500-3000mg), niacin may improve HDL cholesterol. This effect is dose-dependent and not expected at typical supplement doses.
Essential coenzyme (NAD/NADP) in hundreds of metabolic reactions.
At 400mg/day (far above RDA of 1.3mg), riboflavin may reduce migraine frequency. Effect is dose-dependent and not expected at typical supplement doses.
Curcumin has anti-inflammatory properties in clinical studies, though bioavailability is low without enhanced formulations (piperine, liposomal, etc.).
Curcumin may reduce joint pain and inflammation in osteoarthritis. Effects depend on bioavailability — enhanced forms (BCM-95, Meriva, piperine) show better results than standard curcumin.
Curcumin has anti-inflammatory properties in clinical studies, though bioavailability is low without enhanced formulations (piperine, liposomal, etc.).
Curcumin may reduce joint pain and inflammation in osteoarthritis. Effects depend on bioavailability — enhanced forms (BCM-95, Meriva, piperine) show better results than standard curcumin.
No FDA warnings or recalls on file.